Yim Lab at KAIST

Synthetic Biology ∩ Microbiome ∩ Evolution


Welcome to the Yim Lab in the Dept. of Biological Sciences at KAIST.

Our lab explores the vast field of microbiology, encompassing vital areas such as human health, food production, and industrial biotechnology. We are dedicated to unraveling the genetic and microbial components influencing microbiome processes, with the ultimate goal of harnessing microorganisms as living sensors, therapeutics, and manufacturing platforms.

To achieve this, we are pioneering engineering design principles for diverse microbes and microbial communities. Our toolkit includes cutting-edge technologies such as high-throughput DNA synthesis and sequencing, multiplex phenotyping, systems and synthetic biology, animal models, and bioinformatics.

news

Apr 25, 2025 Lab receives an NRF grant as part of a team for biofoundry-based natural product discovery!
Apr 23, 2025 Sung gives a talk at the Institute for Basic Science.
Apr 04, 2025 Our undergrad research team wins the Grand Prize at the KSBB Spring Meeting. Congrats!
Apr 04, 2025 Sung gives a talk at the Korean Society for Biotechnology and Bioengineering Meeting.
Feb 24, 2025 Yelena Kim joins our lab as a high school researcher. Welcome!

selected publications

  1. Exploiting interbacterial antagonism for microbiome engineering
    Yim SS ,  and  Wang HH
    Current Opinion in Biomedical Engineering, 2021
  2. Robust direct digital-to-biological data storage in living cells
    Yim SS ,  McBee RM ,  Song AM ,  Huang Y ,  Sheth RU ,  and  Wang HH
    Nature Chemical Biology, 2021
  3. Multiplex transcriptional characterizations across diverse bacterial species using cell-free systems
    Yim SS+ ,  Johns NI+ ,  Park J ,  Gomes ALC ,  McBee RM ,  Richardson M ,  Ronda C ,  Chen SP ,  Garenne D ,  Noireaux V ,  and  Wang HH
    Molecular Systems Biology, 2019