Yim Lab at KAIST

Synthetic Biology ∩ Microbiome ∩ Evolution

We are the Applied Microbiology and Biotechnology Lab in the Dept. of Biological Sciences at KAIST.

Our research interest lies broadly within microbiology as it applies to a variety of important areas, including human health, food production, and industrial biotechnology. We seek to understand the genetic and microbial factors driving various microbiome processes and transform microorganisms into living sensors, therapeutics, and factories.

Towards this end, we develop engineering design principles for diverse microbes and microbial communities. We utilize a diverse set of tools including high-throughput DNA synthesis and sequencing, multiplex phenotyping, systems and synthetic biology, animal models, and bioinformatics.


Jul 15, 2022 Our lab has officially started in the Department of Biological Sciences at KAIST!

selected publications

  1. Exploiting interbacterial antagonism for microbiome engineering
    Yim, SS, and Wang, HH
    Current Opinion in Biomedical Engineering 2021
  2. Robust direct digital-to-biological data storage in living cells
    Yim, SS, McBee, RM, Song, AM, Huang, Y, Sheth, RU, and Wang, HH
    Nature Chemical Biology 2021
  3. Multiplex transcriptional characterizations across diverse bacterial species using cell-free systems
    Yim, SS+, Johns, NI+, Park, J, Gomes, ALC, McBee, RM, Richardson, M, Ronda, C, Chen, SP, Garenne, D, Noireaux, V, and Wang, HH
    Molecular Systems Biology 2019